Security features in Apple’s new OS make it a little hard to get Timbuktu Pro running for the first time. Here’s how I managed:

1. Copy the Timbuktu Pro folder to your Applications folder.
2. Open terminal and run the following commands:

   xattr -d com.apple.quarantine /Applications/Timbuktu\ Pro/Timbuktu\ Pro.app/
   xattr -d com.apple.quarantine /Applications/Timbuktu\ Pro/Timbuktu\ Pro.app/\
   Contents/SharedSupport/*.app
   open /Applications/Timbuktu\ Pro/Timbuktu\ Pro.app/Contents/SharedSupport/\
   *Host*.app
   open /Applications/Timbuktu\ Pro/Timbuktu\ Pro.app

After that, you should be good to go!